Things you should know about antidepressants

Recently we were discussing antidepressants at the mental health charity I run and I thought it would be worth sharing a few points that came out of the discussion.

Antidepressants are approved by NICE

There is often a lot of scepticism around antidepressants. Irving Kirsch has a whole book about it. However, not only have the drugs been shown to work in clinical trials (I’m not sure how much faith I put in this since All Trials) they are also approved by the National Institute of Clinical Excellence. They are not immune from bias of course, but they generally don’t mess around because the NHS has a limited budget and it’s their job to make sure it is spent on stuff that works.

Antidepressants are trial and error

There are a number of different drugs on the market, some of which do different things and at different doses. These affect people in different ways. That means that what helps some people might not help others, and what gives some people side effects will be fine for others.

It also means that your prescription is trial and error. There is a good chance the first one you get prescribed will not work, either because it is the wrong drug or because you need a different dose.

That means if the first thing you try does not work, try not to get disheartened.

A side effect of antidepressants is suicide

April is suicide month sadly. More people kill themselves in April than any other month. The working theory is that the improved weather conditions provide people suffering from depression to go out and doing something. Unfortunately, this something is sometimes taking their own life.

If true, this would also explain why one of the side effects of antidepressants is suicide. Luckily the limited data available on it suggests that if you inform patients to expect these feelings and be aware of them you mitigate the risk.

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This entry was posted on Sunday, April 26th, 2015 at 10:20 am and is filed under Foundation, Health & Wellbeing. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed.